Presented to the Association of Surgeons of Great Britain and Ireland International Surgical Congress, Bournemouth, UK, May 2008, and published in abstract form as Br J Surg 2008; 95(Suppl 3): 192
Randomized Clinical Trial
Randomized clinical trial of radiofrequency ablation or conventional high ligation and stripping for great saphenous varicose veins†
Article first published online: 24 DEC 2009
Copyright © 2009 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
British Journal of Surgery
Volume 97, Issue 3, pages 328–336, March 2010
How to Cite
Subramonia, S. and Lees, T. (2010), Randomized clinical trial of radiofrequency ablation or conventional high ligation and stripping for great saphenous varicose veins. Br J Surg, 97: 328–336. doi: 10.1002/bjs.6867
- Issue published online: 5 FEB 2010
- Article first published online: 24 DEC 2009
- Manuscript Accepted: 24 AUG 2009
This randomized clinical trial compared early outcomes after radiofrequency ablation (RFA) and conventional surgery for varicose veins.
Consecutive patients with symptomatic varicose veins due to isolated great saphenous vein (GSV) incompetence and suitable for RFA were randomized to either RFA or conventional surgery (saphenofemoral disconnection and stripping). Clinical, radiological and patient-based outcomes were recorded at 1 and 5 weeks after intervention.
RFA resulted in successful obliteration of the GSV in all 47 patients. Complete above-knee stripping was unsuccessful in seven of 41 patients. RFA took longer than conventional surgery: median interquartile range 76 (67–84) versus 48 (39–54) min; P < 0·001. Patients returned to their normal activities significantly earlier after RFA (median 3 (2–5) versus 12·5 (4–21) days; P < 0·001). Postoperative pain was significantly less after RFA (median score on visual analogue scale 1·70 (0·50–4·30) versus 4·0 (2·35–6·05); P = 0·001). Patient satisfaction, quality of life improvement and analgesic requirements significantly favoured RFA.
RFA took longer to perform but resulted in a significantly better early outcome than conventional surgery in suitable patients with great saphenous varicose veins. Registration number: ISRCTN29015169 (http://www.controlled-trials.com). Copyright © 2009 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.