A modeling and simulation approach to the study of metabolic control analysis

Authors

  • Carlos Rodríguez-Caso,

    1. Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Universidad de Málaga, E-29071 Málaga, Spain
    Search for more papers by this author
  • Francisca Sánchez-Jiménez,

    1. Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Universidad de Málaga, E-29071 Málaga, Spain
    Search for more papers by this author
  • Miguel Ángel Medina

    Corresponding author
    1. Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Universidad de Málaga, E-29071 Málaga, Spain
    • Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Universidad de Málaga, E-29071 Málaga, Spain Tel.: 34-95-2137132; Fax: 34-95-2132000
    Search for more papers by this author

  • This work was supported by funds from the Andalusian Government (to the CVI-267 Group) and from the Spanish Ministry for Science and Technology.

Abstract

Metabolic control analysis has contributed to the rapid advance in our understanding of metabolic regulation. However, up to now this topic has not been covered properly in biochemistry courses. This work reports the development and implementation of a practical lesson on metabolic control analysis using modeling and simulation.

The abbreviation used is: MCA, metabolic control analysis.

Ancillary