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Article
Methionine and derivatives: Exploring chirality at sulfur
Article first published online: 3 NOV 2006
DOI: 10.1002/bmb.2005.49403304274
Copyright © 2005 International Union of Biochemistry and Molecular Biology, Inc.
1539-3429/asset/cover.gif?v=1&s=fa4eec691a239b2ca4ee33a2b67e6356cc6d82fb "Biochemistry and Molecular Biology Education")
Additional Information
How to Cite
Bentley, R. (2005), Methionine and derivatives: Exploring chirality at sulfur. Biochem. Mol. Biol. Educ., 33: 274–276. doi: 10.1002/bmb.2005.49403304274
Publication History
- Issue published online: 3 NOV 2006
- Article first published online: 3 NOV 2006
- Manuscript Revised: 27 JAN 2005
- Manuscript Received: 18 NOV 2004
- Abstract
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Keywords:
- S-Adenosylmethionine;
- methionine S-oxide;
- methionine sulfoximine;
- chiral sulfur
Abstract
Chiral molecules, both small and large, play important roles in biochemistry, molecular biology, and related biosciences. The central position of carbon atoms in determining chirality has received considerable attention. Less well known is the fact that chirality is also possible for sulfur atoms in certain compounds. This article introduces the role of sulfur chirality in metabolic reactions by considering methionine derivatives with chiral sulfur atoms, S-adenosylmethionine and its decarboxylated product, methionine S-oxide, and methionine sulfoximine.