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Keywords:

  • Cellular biology;
  • molecular biology;
  • molecular visualization;
  • textbook;
  • diagrams

Abstract

Diverse biological data may be used to create illustrations of molecules in their cellular context. I describe the scientific results that support a recent textbook illustration of an Escherichia coli cell. The image magnifies a portion of the bacterium at one million times, showing the location and form of individual macromolecules. Results from biochemistry, electron microscopy, and X-ray crystallography were used to create the image.