Problem-solving Test: Analysis of DNA Damage Recognizing Proteins in Yeast and Human Cells


Address for correspondence to: Department of Medical Biology, Medical School, University of Pécs, H-7624 Pécs, Hungary. E-mail:


Terms to be familiar with before you start to solve the test: DNA repair, germline mutation, somatic mutation, inherited disease, cancer, restriction endonuclease, radioactive labeling, [α-32P]ATP, [γ-32P]ATP, DNA ligase, polynucleotide kinase, DNA polymerase, terminal transferase, DNA helicase, UV-irradiation, pyrimidine dimer, base modifications, mismatch, polyacrylamide gel electrophoresis, autoradiography, molecular hybridization, satellite DNA, nucleosomes. © 2012 by The International Union of Biochemistry and Molecular Biology, 41(1):52–54, 2013