Neuromagnetic activation following active and passive finger movements
Article first published online: 17 FEB 2013
© 2013 The Authors. Brain and Behavior published by Wiley Periodicals, Inc.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Brain and Behavior
Volume 3, Issue 2, pages 178–192, March 2013
How to Cite
Onishi, H., Sugawara, K., Yamashiro, K., Sato, D., Suzuki, M., Kirimoto, H., Tamaki, H., Murakami, H. and Kameyama, S. (2013), Neuromagnetic activation following active and passive finger movements. Brain and Behavior, 3: 178–192. doi: 10.1002/brb3.126
- Issue published online: 14 MAR 2013
- Article first published online: 17 FEB 2013
- Manuscript Accepted: 15 JAN 2013
- Manuscript Revised: 31 DEC 2012
- Manuscript Received: 5 NOV 2012
- Japan Society for the Promotion of Science
- Advanced Research from the Niigata University of Health and Welfare
- MEG ;
- MRCF ;
- PPC ;
- SEF ;
The detailed time courses of cortical activities and source localizations following passive finger movement were studied using whole-head magnetoencephalography (MEG). We recorded motor-related cortical magnetic fields following voluntary movement and somatosensory-evoked magnetic fields following passive movement (PM) in 13 volunteers. The most prominent movement-evoked magnetic field (MEF1) following active movement was obtained approximately 35.3 ± 8.4 msec after movement onset, and the equivalent current dipole (ECD) was estimated to be in the primary motor cortex (Brodmann area 4). Two peaks of MEG response associated with PM were recorded from 30 to 100 msec after movement onset. The earliest component (PM1) peaked at 36.2 ± 8.2 msec, and the second component (PM2) peaked at 86.1 ± 12.1 msec after movement onset. The peak latency and ECD localization of PM1, estimated to be in area 4, were the same as those of the most prominent MEF following active movement. ECDs of PM2 were estimated to be not only in area 4 but also in the supplementary motor area (SMA) and the posterior parietal cortex (PPC) over the hemisphere contralateral to the movement, and in the secondary somatosensory cortex (S2) of both hemispheres. The peak latency of each source activity was obtained at 54–109 msec in SMA, 64–114 msec in PPC, and 84–184 msec in the S2. Our results suggest that the magnetic waveforms at middle latency (50–100 msec) after PM are different from those after active movement and that these waveforms are generated by the activities of several cortical areas, that is, area 4 and SMA, PPC, and S2. In this study, the time courses of the activities in SMA, PPC, and S2 accompanying PM in humans were successfully recorded using MEG with a multiple dipole analysis system.