Psychopathy is thought by many to be an untreatable disorder. This article puts the treatment of psychopathy into historical context and reviews research on the treatment of the disorder with adults (K = 8) and youth (K = 5). Findings indicate that treatment for adults shows low to moderate success with three of eight studies demonstrating treatment gains. Treatment of youth appears to be more promising with six of eight studies showing treatment benefits. Although less than optimal success rates with adults, we suggest that bright line distinctions regarding the treatability of those with psychopathic characteristics from non-psychopathic individuals are inappropriate at this time. We conclude with directions for future research and briefly introduce the mental models approach for the treatment of psychopathy in youths. Copyright © 2010 John Wiley & Sons, Ltd.