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Additional Supporting Information may be found in the online version of this article.

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BTPR_734_sm_SuppFig1.ppt150KFigure S1. Analytical data of aging on lees in EC1118 and EKD-13. Glucose, ethanol and glycerol contents are provided in % (w/v; g/L).
BTPR_734_sm_SuppFig2.ppt85KFigure S2. Analytical data of monitored fermentation in EC1118 and EKD-13. Panel A): Evolution of the cell population and the accumulated CO2 released. Panel B): Glucose, ethanol and glycerol contents (% w/v; g/L). Panel C): Mannoproteins released. Ranges of ± 1 standard deviation from the mean are represented. Values for EKD-13 are significantly higher than for EC1118 (p<0.05) in all sample points.
BTPR_734_sm_SuppFig3.ppt265KFigure S3. Tolerance to osmotic stress (1 M sorbitol), oxidative stress (5, 10 mM H<INF>2</INF>O<INF>2</INF>), and growth on glycerol, of cells from the strains EC1118, EKD-13, BY4743 and ΔKNR4 pre-grown to exponential phase (panel A). Growth on glycerol of cells from the strains EC1118, EKD-13, BY4743 and ΔKNR4 pre-grown to stationary phase (panel B).
BTPR_734_sm_SuppTab1.doc438KSupplementary table 1. Analysis of regulatory associations between transcription factors and target genes in this study using the YEASTRACT database. The panel A shows the enrichment on genes overrepresented in EKD-13 strain and the panel B the enrichment in EC1118 strain, both for mid- exponential growth phase. The panel C shows the enrichment on genes overrepresented in EKD-13 strain and the panel D the enrichment in EC1118 strain, both for stationary growth phase. The probability was assessed by the Fisher's exact test (significantly difference, p-value<0.05).

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