Biotechnology Progress

Copyright © 2013 American Institute of Chemical Engineers

Cover image for Vol. 28 Issue 4

July/August 2012

Volume 28, Issue 4

Pages 893–1117

  1. Commentary: Biocatalysts and Bioreactor Design

    1. Top of page
    2. Commentary: Biocatalysts and Bioreactor Design
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Erratum
    1. You have free access to this content
      Energy, wealth, and human development: Why and how biomass pretreatment research must improve (pages 893–898)

      Bruce E. Dale and Rebecca G. Ong

      Article first published online: 16 JUL 2012 | DOI: 10.1002/btpr.1575

  2. Bioseparations and Downstream Processing

    1. Top of page
    2. Commentary: Biocatalysts and Bioreactor Design
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Erratum
    1. State-of-the-art in downstream processing of monoclonal antibodies: Process trends in design and validation (pages 899–916)

      P. A. Marichal-Gallardo and M. M. Álvarez

      Article first published online: 26 JUN 2012 | DOI: 10.1002/btpr.1567

  3. Applied Cellular Physiology and Metabolic Engineering

    1. Top of page
    2. Commentary: Biocatalysts and Bioreactor Design
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Erratum
    1. The lactate conundrum in wound healing: Clinical and experimental findings indicate the requirement for a rapid point-of-care diagnostic (pages 917–924)

      Stephen Britland, Oliver Ross-Smith, Humzah Jamil, Annie G. Smith, Kath Vowden and Peter Vowden

      Article first published online: 18 JUN 2012 | DOI: 10.1002/btpr.1561

  4. Biocatalysts and Bioreactor Design

    1. Top of page
    2. Commentary: Biocatalysts and Bioreactor Design
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Erratum
    1. Coexpression of molecular chaperone enhances activity and export of organophosphorus hydrolase in Escherichia coli (pages 925–930)

      Dong Gyun Kang, Chang Sup Kim, Jeong Hyun Seo, Im Gyu Kim, Suk Soon Choi, Jeong Hyub Ha, Soo Wan Nam, Geunbae Lim and Hyung Joon Cha

      Article first published online: 8 JUN 2012 | DOI: 10.1002/btpr.1556

    2. Effect of initial bacteria concentration on hydrogen gas production from cheese whey powder solution by thermophilic dark fermentation (pages 931–936)

      Fikret Kargi, Nur Seza Eren and Serpil Ozmihci

      Article first published online: 18 JUN 2012 | DOI: 10.1002/btpr.1558

    3. Crosslinked aggregates of Rhizopus oryzae lipase as industrial biocatalysts: Preparation, optimization, characterization, and application for enantioselective resolution reactions (pages 937–945)

      Funda Kartal and Ali Kilinc

      Article first published online: 26 JUN 2012 | DOI: 10.1002/btpr.1571

    4. Thermal stabilization of psychrophilic enzymes: A case study of the cold-active hormone-sensitive lipase from Psychrobacter sp. TA144 (pages 946–952)

      Concetta De Santi, Lorenzo Durante, Pompea Del Vecchio, Maria Luisa Tutino, Ermenegilda Parrilli and Donatella de Pascale

      Article first published online: 2 JUL 2012 | DOI: 10.1002/btpr.1574

    5. Cross-linked protein complex exhibiting asymmetric oxidation activities in the absence of added cofactor (pages 953–961)

      Hiroyuki Nagaoka, Keisuke Udagawa and Kohtaro Kirimura

      Article first published online: 20 JUL 2012 | DOI: 10.1002/btpr.1580

  5. Bioseparations and Downstream Processing

    1. Top of page
    2. Commentary: Biocatalysts and Bioreactor Design
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Erratum
    1. Selective separation of biobutanol from acetone–butanol–ethanol fermentation broth by means of sorption methodology based on a novel macroporous resin (pages 962–972)

      Xiaoqing Lin, Jinglan Wu, Xiaohong Jin, Jiansheng Fan, Renjie Li, Qingshi Wen, Wenbin Qian, Dong Liu, Xiaochun Chen, Yong Chen, Jingjing Xie, Jianxin Bai and Hanjie Ying

      Article first published online: 8 JUN 2012 | DOI: 10.1002/btpr.1553

    2. Human collagen isolated from adipose tissue (pages 973–980)

      Beob Soo Kim, Ji Suk Choi, Jae Dong Kim, Hwa In Yoon, Young Chan Choi and Yong Woo Cho

      Article first published online: 8 JUN 2012 | DOI: 10.1002/btpr.1555

    3. Phage-derived fully human antibody scFv fragment directed against human vascular endothelial growth factor receptor 2 blocked its interaction with VEGF (pages 981–989)

      Juan Zhang, Haixin Li, Xiuyun Wang, Haidi Qi, Xiaoniu Miao, Tao Zhang, Guosheng Chen and Min Wang

      Article first published online: 18 JUN 2012 | DOI: 10.1002/btpr.1559

    4. Liquid–liquid extraction for recovery of paclitaxel from plant cell culture: Solvent evaluation and use of extractants for partitioning and selectivity (pages 990–997)

      Timothy J. McPartland, Rohan A. Patil, Michael F. Malone and Susan C. Roberts

      Article first published online: 18 JUN 2012 | DOI: 10.1002/btpr.1562

    5. An integrated process for removing the inhibitors of the prehydrolysis liquor of kraft-based dissolving pulp process via cationic polymer treatment (pages 998–1004)

      Abrar Saeed, Pedram Fatehi and Yonghao Ni

      Article first published online: 22 JUN 2012 | DOI: 10.1002/btpr.1563

    6. Purification of IgG and albumin from human plasma by aqueous two phase system fractionation (pages 1005–1011)

      Mariángela Vargas, Álvaro Segura, María Herrera, Mauren Villalta, Yamileth Angulo, José María Gutiérrez, Guillermo León and Thierry Burnouf

      Article first published online: 22 JUN 2012 | DOI: 10.1002/btpr.1565

    7. Application of a 22L scale membrane bioreactor and cross-flow ultrafiltration to obtain purified chondroitin (pages 1012–1018)

      Chiara Schiraldi, Alberto Alfano, Donatella Cimini, Mario De Rosa, Andrea Panariello, Odile F. Restaino and Mario De Rosa

      Article first published online: 22 JUN 2012 | DOI: 10.1002/btpr.1566

    8. Decisional tool to assess current and future process robustness in an antibody purification facility (pages 1019–1028)

      Adam Stonier, Ana Sofia Simaria, Martin Smith and Suzanne S. Farid

      Article first published online: 22 JUN 2012 | DOI: 10.1002/btpr.1569

    9. An ultra scale-down approach to assess the impact of the choice of recombinant P. pastoris strain on dewatering performance in centrifuges (pages 1029–1036)

      Adriana G. Lopes, Nadia Khan, John Liddell and Eli Keshavarz-Moore

      Article first published online: 20 JUL 2012 | DOI: 10.1002/btpr.1570

    10. Host cell protein adsorption characteristics during protein a chromatography (pages 1037–1044)

      Richard D. R. Tarrant, M. Lourdes Velez-Suberbie, Andrew S. Tait, C. Mark Smales and Daniel G. Bracewell

      Article first published online: 20 JUL 2012 | DOI: 10.1002/btpr.1581

  6. Cell Culture and Tissue Engineering

    1. Top of page
    2. Commentary: Biocatalysts and Bioreactor Design
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Erratum
    1. Dynamics of diffusivity and pressure drop in flow-through and parallel-flow bioreactors during tissue regeneration (pages 1045–1054)

      Jagdeep T. Podichetty, Dhananjay V. Dhane and Sundararajan V. Madihally

      Article first published online: 21 MAY 2012 | DOI: 10.1002/btpr.1547

    2. 3,4-dihydroxy-L-phenylalanine as a cell adhesion molecule in serum-free cell culture (pages 1055–1060)

      Wan-Geun La, Suk Ho Bhang, Jung-Youn Shin, Hee Hun Yoon, Jooyeon Park, Hee Seok Yang, Seung-Ho Yu, Yung-Eun Sung and Byung-Soo Kim

      Article first published online: 18 JUN 2012 | DOI: 10.1002/btpr.1560

    3. Development toward rapid and efficient screening for high performance hydrolysate lots in a recombinant monoclonal antibody manufacturing process (pages 1061–1068)

      Ying Luo and Karisa M. Pierce

      Article first published online: 22 JUN 2012 | DOI: 10.1002/btpr.1568

    4. Quantitative methods to characterize morphological properties of cell lines (pages 1069–1078)

      Annalaura Mancia, John T. Elliott, Michael Halter, Kiran Bhadriraju, Alessandro Tona, Tighe A. Spurlin, Bobby L. Middlebrooks, John E. Baatz, Gregory W. Warr and Anne L. Plant

      Article first published online: 26 JUN 2012 | DOI: 10.1002/btpr.1564

    5. Surface-based cryopreservation strategies for human embryonic stem cells: A comparative study (pages 1079–1087)

      Rita Malpique, Rui Tostões, Axel F. J. Beier, Margarida Serra, Catarina Brito, Julia C. Schulz, Petter Björquist, Heiko Zimmermann and Paula M. Alves

      Article first published online: 2 JUL 2012 | DOI: 10.1002/btpr.1572

  7. Formulation and Engineering of Biomaterials

    1. Top of page
    2. Commentary: Biocatalysts and Bioreactor Design
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Erratum
    1. Gene delivery using biodegradable polyelectrolyte microcapsules prepared through the layer-by-layer technique (pages 1088–1094)

      José L. Santos, Alireza Nouri, Tiago Fernandes, João Rodrigues and Helena Tomás

      Article first published online: 20 JUL 2012 | DOI: 10.1002/btpr.1576

  8. Process Sensing and Control

    1. Top of page
    2. Commentary: Biocatalysts and Bioreactor Design
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Erratum
    1. Optimization of a Saccharomyces cerevisiae fermentation process for production of a therapeutic recombinant protein using a multivariate bayesian approach (pages 1095–1105)

      Zhibiao Fu, Julie Leighton, Aili Cheng, Edward Appelbaum and Juan C. Aon

      Article first published online: 18 JUN 2012 | DOI: 10.1002/btpr.1557

    2. SYBR green real time-polymerase chain reaction as a rapid and alternative assay for the efficient identification of all existing Escherichia coli biotypes approved directly in wastewater samples (pages 1106–1113)

      Massimiliano Chetta, Valeria Bafunno, Rosalba Grillo, Antonio Mele, Pietro Lo Perfido, Michele Notarnicola, Francesco Cellini and Rosa Anna Cifarelli

      Article first published online: 16 JUL 2012 | DOI: 10.1002/btpr.1573

  9. Erratum

    1. Top of page
    2. Commentary: Biocatalysts and Bioreactor Design
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Erratum
    1. You have free access to this content
      Erratum (page 1114)

      Article first published online: 23 JUL 2012 | DOI: 10.1002/btpr.1589

      This article corrects:

      Influence of growth temperature on the production of antibody Fab fragments in different microbes: A host comparative analysis

      Vol. 27, Issue 1, 38–46, Article first published online: 23 DEC 2010

    2. You have free access to this content
      Erratum (pages 1115–1117)

      Article first published online: 27 JUL 2012 | DOI: 10.1002/btpr.1579

      This article corrects:

      Mini-scale bioprocessing systems for highly parallel animal cell cultures

      Vol. 28, Issue 3, 595–607, Article first published online: 21 MAY 2012

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