Biotechnology Progress

Copyright © 2013 American Institute of Chemical Engineers

Cover image for Vol. 28 Issue 5

September/October 2012

Volume 28, Issue 5

Pages 1119–1388

  1. Applied Cellular Physiology and Metabolic Engineering

    1. Top of page
    2. Applied Cellular Physiology and Metabolic Engineering
    3. Biocatalysts and Bioreactor Design
    4. Bioseparations and Downstream Processing
    5. Cell Culture and Tissue Engineering
    6. Formulation and Engineering of Biomaterials
    7. Process Sensing and Control
    8. Cell Culture and Tissue Engineering
    1. Rational optimization of culture conditions for the most efficient ethanol production in Scheffersomyces stipitis using design of experiments (pages 1119–1125)

      Pornkamol Unrean and Nhung H. A. Nguyen

      Article first published online: 31 JUL 2012 | DOI: 10.1002/btpr.1595

    2. Genomic analysis of a hybridoma batch cell culture metabolic status in a standard laboratory 5 L bioreactor (pages 1126–1137)

      Bhargavi Kondragunta, Jing Han, Bharat H Joshi, Kurt A. Brorson, Raj K. Puri, Shaunak Uplekar, Antonio R. Moreira and Govind Rao

      Article first published online: 18 SEP 2012 | DOI: 10.1002/btpr.1605

    3. Bioreactor environment-sensitive sentinel genes as novel metrics for cell culture scale-down comparability (pages 1138–1151)

      Bhargavi Kondragunta, Bharat H. Joshi, Jing Han, Kurt A. Brorson, Raj K. Puri, Antonio R. Moreira and Govind Rao

      Article first published online: 18 SEP 2012 | DOI: 10.1002/btpr.1606

    4. Droplet aerodynamics, cellular uptake, and efficacy of a nebulizable corticosteroid nanosuspension are superior to a micronized dosage form (pages 1152–1159)

      Stephen Britland, Wayne Finter, Henry Chrystyn, Donald Eagland and Mohamed E. Abdelrahim

      Article first published online: 21 SEP 2012 | DOI: 10.1002/btpr.1616

  2. Biocatalysts and Bioreactor Design

    1. Top of page
    2. Applied Cellular Physiology and Metabolic Engineering
    3. Biocatalysts and Bioreactor Design
    4. Bioseparations and Downstream Processing
    5. Cell Culture and Tissue Engineering
    6. Formulation and Engineering of Biomaterials
    7. Process Sensing and Control
    8. Cell Culture and Tissue Engineering
    1. Exacting predictions by cybernetic model confirmed experimentally: Steady state multiplicity in the chemostat (pages 1160–1166)

      Jin Il Kim, Hyun-Seob Song, Sunil R. Sunkara, Arvind Lali and Doraiswami Ramkrishna

      Article first published online: 16 JUL 2012 | DOI: 10.1002/btpr.1583

    2. Genetically engineered Escherichia coli FBR5: Part I. Comparison of high cell density bioreactors for enhanced ethanol production from xylose (pages 1167–1178)

      N. Qureshi, B. S. Dien, S. Liu, B. C. Saha, R. Hector, M. A. Cotta and S. Hughes

      Article first published online: 20 JUL 2012 | DOI: 10.1002/btpr.1585

    3. Genetically engineered Escherichia coli FBR5: Part II. Ethanol production from xylose and simultaneous product recovery (pages 1179–1185)

      N. Qureshi, B. S. Dien, S. Liu, B. C. Saha, M. A. Cotta, S. Hughes and R. Hector

      Article first published online: 20 JUL 2012 | DOI: 10.1002/btpr.1584

    4. A robust methodology for kinetic model parameter estimation for biocatalytic reactions (pages 1186–1196)

      Naweed Al-Haque, Paloma A. Santacoloma, Watson Neto, Pär Tufvesson, Rafiqul Gani and John M. Woodley

      Article first published online: 25 JUL 2012 | DOI: 10.1002/btpr.1588

    5. Modeling the angiotensin-converting enzyme inhibitory activity of peptide mixtures obtained from cheese whey hydrolysates using concentration–response curves (pages 1197–1206)

      Natalia Estévez, Pablo Fuciños, Ana C. Sobrosa, Lorenzo Pastrana, Nelson Pérez and M. Luisa Rúa

      Article first published online: 26 JUL 2012 | DOI: 10.1002/btpr.1587

    6. Enhancement of the enzymatic digestibility of sugarcane bagasse by steam pretreatment impregnated with hydrogen peroxide (pages 1207–1217)

      Sarita Cândida Rabelo, Carlos Eduardo Vaz Rossell, George Jackson de Moraes Rocha and Guido Zacchi

      Article first published online: 27 JUL 2012 | DOI: 10.1002/btpr.1593

    7. Synthesis of monoacylglycerol containing pinolenic acid via stepwise esterification using a cold active lipase (pages 1218–1224)

      Young-Gil Pyo, Seung In Hong, Yangha Kim, Byung Hee Kim and In-Hwan Kim

      Article first published online: 27 JUL 2012 | DOI: 10.1002/btpr.1596

    8. Laccase for biobleaching of eucalypt kraft pulp by means of a modified industrial bleaching sequence (pages 1225–1231)

      D. Moldes and T. Vidal

      Article first published online: 31 JUL 2012 | DOI: 10.1002/btpr.1594

    9. Immobilization/stabilization of acid urease on Eupergit® supports (pages 1232–1244)

      Nadia Bortone, Marcello Fidaleo and Mauro Moresi

      Article first published online: 31 JUL 2012 | DOI: 10.1002/btpr.1598

    10. Biomass production from Trichoderma viride in nonconventional oat medium (pages 1245–1250)

      F. L. Motta and M. H. A. Santana

      Article first published online: 28 AUG 2012 | DOI: 10.1002/btpr.1578

    11. Biotransformation of 2,6-diaminopurine nucleosides by immobilized Geobacillus stearothermophilus (pages 1251–1256)

      Eliana C. De Benedetti, Cintia W. Rivero, Claudia N. Britos, Mario E. Lozano and Jorge A. Trelles

      Article first published online: 28 AUG 2012 | DOI: 10.1002/btpr.1602

    12. Engineering the acceptor specificity of trehalose phosphorylase for the production of trehalose analogs (pages 1257–1262)

      Jef Van der Borght, Wim Soetaert and Tom Desmet

      Article first published online: 28 AUG 2012 | DOI: 10.1002/btpr.1609

    13. Beneficial effect of protracted sterilization of lentils on phytase production by Aspergillus ficuum in solid state fermentation (pages 1263–1270)

      Patrick Bennett and Shang-Tian Yang

      Article first published online: 18 SEP 2012 | DOI: 10.1002/btpr.1603

    14. Structure-based replacement of methionine residues at the catalytic domains with serine significantly improves the oxidative stability of alkaline amylase from alkaliphilic Alkalimonas amylolytica (pages 1271–1277)

      Haiquan Yang, Long Liu, Jianghua Li, Guocheng Du and Jian Chen

      Article first published online: 21 SEP 2012 | DOI: 10.1002/btpr.1611

    15. Improvement of Photorhabdus temperata bioinsecticides production in low-cost media through adequate fermentation technology (pages 1278–1284)

      Wafa Jallouli, Samir Jaoua and Nabil Zouari

      Article first published online: 27 SEP 2012 | DOI: 10.1002/btpr.1612

  3. Bioseparations and Downstream Processing

    1. Top of page
    2. Applied Cellular Physiology and Metabolic Engineering
    3. Biocatalysts and Bioreactor Design
    4. Bioseparations and Downstream Processing
    5. Cell Culture and Tissue Engineering
    6. Formulation and Engineering of Biomaterials
    7. Process Sensing and Control
    8. Cell Culture and Tissue Engineering
    1. Investigating the use of column inserts to achieve better chromatographic bed support (pages 1285–1291)

      Tian Lan, Spyridon Gerontas, Graeme R. Smith, John Langdon, John M. Ward and Nigel J. Titchener-Hooker

      Article first published online: 27 JUL 2012 | DOI: 10.1002/btpr.1597

    2. Strategic assay deployment as a method for countering analytical bottlenecks in high throughput process development: Case studies in ion exchange chromatography (pages 1292–1302)

      Spyridon Konstantinidis, Eva Heldin, Sunil Chhatre, Ajoy Velayudhan and Nigel Titchener-Hooker

      Article first published online: 31 JUL 2012 | DOI: 10.1002/btpr.1591

    3. A protocol to remove colored metabolites and other inhibitors from plant tissues to facilitate RNA isolation suitable for downstream applications (pages 1303–1307)

      Ravi S. Singh and Sanjay Kumar

      Article first published online: 17 AUG 2012 | DOI: 10.1002/btpr.1577

    4. Chemometrics applications in biotechnology processes: Predicting column integrity and impurity clearance during reuse of chromatography resin (pages 1308–1314)

      Anurag S. Rathore, Shachi Mittal, Scott Lute and Kurt Brorson

      Article first published online: 18 SEP 2012 | DOI: 10.1002/btpr.1610

  4. Cell Culture and Tissue Engineering

    1. Top of page
    2. Applied Cellular Physiology and Metabolic Engineering
    3. Biocatalysts and Bioreactor Design
    4. Bioseparations and Downstream Processing
    5. Cell Culture and Tissue Engineering
    6. Formulation and Engineering of Biomaterials
    7. Process Sensing and Control
    8. Cell Culture and Tissue Engineering
    1. The impact of fabrication parameters and substrate stiffness in direct writing of living constructs (pages 1315–1320)

      Annalisa Tirella and Arti Ahluwalia

      Article first published online: 23 JUL 2012 | DOI: 10.1002/btpr.1586

    2. Rapid, in situ detection of Agrobacterium tumefaciens attachment to leaf tissue (pages 1321–1328)

      Christopher W. Simmons, N. Nitin and Jean S. VanderGheynst

      Article first published online: 28 AUG 2012 | DOI: 10.1002/btpr.1608

    3. Neural stimulation on human bone marrow-derived mesenchymal stem cells by extremely low frequency electromagnetic fields (pages 1329–1335)

      Hyunjin Cho, Young-Kwon Seo, Hee-Hoon Yoon, Soo-Chan Kim, Sung-Min Kim, Kye-Yong Song and Jung-Keug Park

      Article first published online: 18 SEP 2012 | DOI: 10.1002/btpr.1607

  5. Formulation and Engineering of Biomaterials

    1. Top of page
    2. Applied Cellular Physiology and Metabolic Engineering
    3. Biocatalysts and Bioreactor Design
    4. Bioseparations and Downstream Processing
    5. Cell Culture and Tissue Engineering
    6. Formulation and Engineering of Biomaterials
    7. Process Sensing and Control
    8. Cell Culture and Tissue Engineering
    1. New biocomposites based on bioplastic flax fibers and biodegradable polymers (pages 1336–1346)

      Magdalena Wróbel-Kwiatkowska, Magdalena Czemplik, Anna Kulma, Magdalena Żuk, Jacek Kaczmar, Lucyna Dymińska, Jerzy Hanuza, Maciej Ptak and Jan Szopa

      Article first published online: 17 AUG 2012 | DOI: 10.1002/btpr.1599

    2. Cryopreservation of platelets using trehalose: The role of membrane phase behavior during freezing (pages 1347–1354)

      Christiane Gläfke, Maryam Akhoondi, Harriëtte Oldenhof, Harald Sieme and Willem F. Wolkers

      Article first published online: 18 SEP 2012 | DOI: 10.1002/btpr.1600

  6. Process Sensing and Control

    1. Top of page
    2. Applied Cellular Physiology and Metabolic Engineering
    3. Biocatalysts and Bioreactor Design
    4. Bioseparations and Downstream Processing
    5. Cell Culture and Tissue Engineering
    6. Formulation and Engineering of Biomaterials
    7. Process Sensing and Control
    8. Cell Culture and Tissue Engineering
    1. In situ Raman spectroscopy for simultaneous monitoring of multiple process parameters in mammalian cell culture bioreactors (pages 1355–1362)

      Jessica Whelan, Stephen Craven and Brian Glennon

      Article first published online: 20 JUL 2012 | DOI: 10.1002/btpr.1590

    2. Numerical evaluation of lactoperoxidase inactivation during continuous pulsed electric field processing (pages 1363–1375)

      Roman Buckow, Julius Semrau, Qian Sui, Jason Wan and Kai Knoerzer

      Article first published online: 26 JUL 2012 | DOI: 10.1002/btpr.1582

    3. Quantitative analyses of individual sugars in mixture using FRET-based biosensors (pages 1376–1383)

      Jae-Seok Ha, Jongsik Gam, Su-Lim Choi, Ki-Hoon Oh, Hyeon-Su Ro, Jae Jun Song, Chul Soo Shin and Seung-Goo Lee

      Article first published online: 31 JUL 2012 | DOI: 10.1002/btpr.1592

  7. Cell Culture and Tissue Engineering

    1. Top of page
    2. Applied Cellular Physiology and Metabolic Engineering
    3. Biocatalysts and Bioreactor Design
    4. Bioseparations and Downstream Processing
    5. Cell Culture and Tissue Engineering
    6. Formulation and Engineering of Biomaterials
    7. Process Sensing and Control
    8. Cell Culture and Tissue Engineering
    1. Regulation of autocrine fibroblast growth factor-2 signaling by perfusion flow in 3D human mesenchymal stem cell constructs (pages 1384–1388)

      Junho Kim and Teng Ma

      Article first published online: 28 AUG 2012 | DOI: 10.1002/btpr.1604

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