Biotechnology Progress

Cover image for Vol. 30 Issue 6

November/December 2014

Volume 30, Issue 6

Pages 1247–1501

  1. Applied Cellular Physiology and Metabolic Engineering

    1. Top of page
    2. Applied Cellular Physiology and Metabolic Engineering
    3. Biocatalysts and Bioreactor Design
    4. Bioseparations and Downstream Processing
    5. Cell Culture and Tissue Engineering
    6. Formulation and Engineering of Biomaterials
    7. Process Sensing and Control
    8. Bioseparations and Downstream Processing
  2. Biocatalysts and Bioreactor Design

    1. Top of page
    2. Applied Cellular Physiology and Metabolic Engineering
    3. Biocatalysts and Bioreactor Design
    4. Bioseparations and Downstream Processing
    5. Cell Culture and Tissue Engineering
    6. Formulation and Engineering of Biomaterials
    7. Process Sensing and Control
    8. Bioseparations and Downstream Processing
    1. Assessment of mass transfer and mixing in rigid lab-scale disposable bioreactors at low power input levels (pages 1269–1276)

      Gerco van Eikenhorst, Yvonne E. Thomassen, Leo A. van der Pol and Wilfried A. M. Bakker

      Article first published online: 5 SEP 2014 | DOI: 10.1002/btpr.1981

    2. Mechanistic modeling of biodiesel production using a liquid lipase formulation (pages 1277–1290)

      Jason Price, Björn Hofmann, Vanessa T. L. Silva, Mathias Nordblad, John M. Woodley and Jakob K. Huusom

      Article first published online: 16 SEP 2014 | DOI: 10.1002/btpr.1985

  3. Bioseparations and Downstream Processing

    1. Top of page
    2. Applied Cellular Physiology and Metabolic Engineering
    3. Biocatalysts and Bioreactor Design
    4. Bioseparations and Downstream Processing
    5. Cell Culture and Tissue Engineering
    6. Formulation and Engineering of Biomaterials
    7. Process Sensing and Control
    8. Bioseparations and Downstream Processing
    1. Understanding and modeling alternating tangential flow filtration for perfusion cell culture (pages 1291–1300)

      William Kelly, Jennifer Scully, Di Zhang, Gang Feng, Mathew Lavengood, Jason Condon, John Knighton and Ravinder Bhatia

      Article first published online: 6 AUG 2014 | DOI: 10.1002/btpr.1953

    2. Development of a novel affinity chromatography resin for platform purification of lambda fabs (pages 1311–1318)

      Nora Eifler, Giovanni Medaglia, Oliver Anderka, Linus Laurin and Pim Hermans

      Article first published online: 6 AUG 2014 | DOI: 10.1002/btpr.1958

    3. You have full text access to this OnlineOpen article
    4. Maximizing binding capacity for protein A chromatography (pages 1335–1340)

      Sanchayita Ghose, Jennifer Zhang, Lynn Conley, Ryan Caple, Kevin P. Williams and Douglas Cecchini

      Article first published online: 2 SEP 2014 | DOI: 10.1002/btpr.1980

    5. In situ cell retention of a CHO culture by a reverse-flow diafiltration membrane bioreactor (pages 1348–1355)

      Kristina Meier, Suzana Djeljadini, Lars Regestein, Jochen Büchs, Frederike Carstensen, Matthias Wessling, Tanja Holland and Nicole Raven

      Article first published online: 18 SEP 2014 | DOI: 10.1002/btpr.1988

    6. Toward improving selectivity in affinity chromatography with PEGylated affinity ligands: The performance of PEGylated protein A (pages 1364–1379)

      José González-Valdez, Alex Yoshikawa, Justin Weinberg, Jorge Benavides, Marco Rito-Palomares and Todd M. Przybycien

      Article first published online: 18 OCT 2014 | DOI: 10.1002/btpr.1994

    7. You have full text access to this OnlineOpen article
      Development and scale-up of a commercial fed batch refolding process for an anti-CD22 two chain immunotoxin (pages 1380–1389)

      Thomas Linke, Matthew T. Aspelund, Christopher Thompson, Guoling Xi, Andrew Fulton, Michaela Wendeler, Timothy M. Pabst, Xiangyang Wang, William K. Wang, Kripa Ram and Alan K. Hunter

      Article first published online: 2 SEP 2014 | DOI: 10.1002/btpr.1983

  4. Cell Culture and Tissue Engineering

    1. Top of page
    2. Applied Cellular Physiology and Metabolic Engineering
    3. Biocatalysts and Bioreactor Design
    4. Bioseparations and Downstream Processing
    5. Cell Culture and Tissue Engineering
    6. Formulation and Engineering of Biomaterials
    7. Process Sensing and Control
    8. Bioseparations and Downstream Processing
    1. Methodological strategies for transgene copy number quantification in goats (Capra hircus) using real-time PCR (pages 1390–1400)

      Ribrio I. T. P. Batista, Maria C. S. Luciano, Dárcio I. A. Teixeira, Vicente J. F. Freitas, Luciana M. Melo, Lyudmila E. Andreeva, Irina A. Serova and Oleg L. Serov

      Article first published online: 26 JUL 2014 | DOI: 10.1002/btpr.1946

    2. Development of small scale cell culture models for screening poloxamer 188 lot-to-lot variation (pages 1411–1418)

      Haofan Peng, Kaitlyn M. Hall, Blake Clayton, Kelly Wiltberger, Weiwei Hu, Erik Hughes, John Kane, Rachel Ney and Thomas Ryll

      Article first published online: 19 AUG 2014 | DOI: 10.1002/btpr.1967

    3. Cell culture media supplementation of uncommonly used sugars sucrose and tagatose for the targeted shifting of protein glycosylation profiles of recombinant protein therapeutics (pages 1419–1431)

      Patrick Hossler, Sean McDermott, Christopher Racicot, Christopher Chumsae, Haly Raharimampionona, Yu Zhou, David Ouellette, Joseph Matuck, Ivan Correia, John Fann and Jianmin Li

      Article first published online: 19 AUG 2014 | DOI: 10.1002/btpr.1968

    4. Time efficient way to calculate oxygen transfer areas and power input in cylindrical disposable shaken bioreactors (pages 1441–1456)

      Wolf Klöckner, Clemens Lattermann, Franz Pursche, Jochen Büchs, Sören Werner and Dieter Eibl

      Article first published online: 5 SEP 2014 | DOI: 10.1002/btpr.1977

  5. Formulation and Engineering of Biomaterials

    1. Top of page
    2. Applied Cellular Physiology and Metabolic Engineering
    3. Biocatalysts and Bioreactor Design
    4. Bioseparations and Downstream Processing
    5. Cell Culture and Tissue Engineering
    6. Formulation and Engineering of Biomaterials
    7. Process Sensing and Control
    8. Bioseparations and Downstream Processing
  6. Process Sensing and Control

    1. Top of page
    2. Applied Cellular Physiology and Metabolic Engineering
    3. Biocatalysts and Bioreactor Design
    4. Bioseparations and Downstream Processing
    5. Cell Culture and Tissue Engineering
    6. Formulation and Engineering of Biomaterials
    7. Process Sensing and Control
    8. Bioseparations and Downstream Processing
    1. Maximizing recombinant human serum albumin production in a Muts Pichia pastoris strain (pages 1488–1496)

      Muralidhar Mallem, Shannon Warburton, Fang Li, Ishaan Shandil, Adam Nylen, Sehoon Kim, Youwei Jiang, Michael Meehl, Marc d'Anjou, Terrance A. Stadheim and Byung-Kwon Choi

      Article first published online: 16 SEP 2014 | DOI: 10.1002/btpr.1990

  7. Bioseparations and Downstream Processing

    1. Top of page
    2. Applied Cellular Physiology and Metabolic Engineering
    3. Biocatalysts and Bioreactor Design
    4. Bioseparations and Downstream Processing
    5. Cell Culture and Tissue Engineering
    6. Formulation and Engineering of Biomaterials
    7. Process Sensing and Control
    8. Bioseparations and Downstream Processing
    1. Gel filtration chromatography as a method for removing bacterial endotoxin from antibody preparations (pages 1497–1501)

      Anne Serdakowski London, Kasey Mackay, Michael Lihon, Yaqin He and Busola Ruth Alabi

      Article first published online: 7 AUG 2014 | DOI: 10.1002/btpr.1961

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