James Drake (1667–1707) was a renowned physician, anatomist, and writer whose name was recognized throughout London. He was highly involved in the politics of his time and was a well-known pamphleteer. He also delved into comedies and plays. Drake became a fellow of the Royal Society and the College of Physicians before his early death at 40 years of age. He authored one of the most deservedly popular medical treatises of his time, Anthropologia Nova, which remained a valuable resource to physicians and anatomists alike for decades. The present article reviews the contributions of this little known name in the history of anatomy. Clin. Anat. 25:295–298, 2012. © 2011 Wiley Periodicals, Inc.