Charles-Pierre Denonvilliers was one of the most influential and prolific French anatomists and surgeons of the 19th century. Born in Paris and educated at the Paris Faculty of Medicine in 1826, he steadily created a reputation for himself in the field of medicine. Starting in 1833, Denonvilliers lectured with exquisite clarity and scientific accuracy in surgery and anatomy. Not only did he make a name for himself in this arena but also as an anatomist of high caliber based on his anatomical dissections and presentations. These talents and skills afforded Denonvilliers the opportunity to acquire different other titles and positions throughout his career. His reputation as a plastic surgeon, anatomist, and lecturer coupled with his status and influence made his sudden death in 1872, an occasion of bereavement for the French medical profession. Clin. Anat. 26:788–792, 2013. © 2012 Wiley Periodicals, Inc.