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cam435-sup-0001-FigureS1.pptxapplication/mspowerpoint11610KFigure S1. Nisin treatment does not alter liver and kidney histological morphology and preloading with nisin reduces tumor volume. (A) Representative hematoxylin and eosin staining of liver and kidney tissue sections from mice administered 150 mg/kg per day of nisin for 3 weeks (n = 3 mice). (B) Tumor volumes for mice administered water (CTRL) or nisin (200 mg/kg per day) for 3 weeks pre- and postinjection of UM-SCC-17B cells. P values for each data set are indicated individually.
cam435-sup-0002-FigureS2.pptxapplication/mspowerpoint11610KFigure S2. Nisin inhibits Cdc2 phosphorylation but promotes PARP and caspase-3 cleavage. Immunoblots showing (A) Cdc2 and p-Cdc2 and (B) active/cleaved PARP and caspase-3 expression in control (CTRL) and nisin-treated UM-SCC-17B cells. β-Actin served as a loading control.

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