Cannabidiol – Recent Advances

Authors

  • Raphael Mechoulam,

    1. Department of Medicinal Chemistry and Natural Products, Hebrew University Medical Faculty, Jerusalem 91120, Israel (phone: +972-2-6758643)
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  • Maximilian Peters,

    1. Department of Medicinal Chemistry and Natural Products, Hebrew University Medical Faculty, Jerusalem 91120, Israel (phone: +972-2-6758643)
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  • Eric Murillo-Rodriguez,

    1. Departamiento de Neurociencias, Instituto de Fisiologia Celular, Ciudad Universitaria, Circuito Interior, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
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  • Lumír O. Hanuš

    1. Department of Medicinal Chemistry and Natural Products, Hebrew University Medical Faculty, Jerusalem 91120, Israel (phone: +972-2-6758643)
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Abstract

The aim of this review is to present some of the recent publications on cannabidiol (CBD; 2), a major non-psychoactive constituent of Cannabis, and to give a general overview. Special emphasis is laid on biochemical and pharmacological advances, and on novel mechanisms recently put forward, to shed light on some of the pharmacological effects that can possibly be rationalized through these mechanisms. The plethora of positive pharmacological effects observed with CBD make this compound a highly attractive therapeutic entity.

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