Head of the Department.
Oral vitamin C and E combination modulates blood lipid peroxidation and antioxidant vitamin levels in maximal exercising basketball players
Article first published online: 7 MAY 2010
Copyright © 2010 John Wiley & Sons, Ltd.
Cell Biochemistry and Function
Volume 28, Issue 4, pages 300–305, June 2010
How to Cite
Nazıroğlu, M., Kılınç, F., Uğuz, A. C., Çelik, Ö., Bal, R., Butterworth, P. J. and Baydar, M. L. (2010), Oral vitamin C and E combination modulates blood lipid peroxidation and antioxidant vitamin levels in maximal exercising basketball players. Cell Biochem. Funct., 28: 300–305. doi: 10.1002/cbf.1657
- Issue published online: 26 MAY 2010
- Article first published online: 7 MAY 2010
- Manuscript Revised: 10 FEB 2010
- Manuscript Accepted: 10 FEB 2010
- Manuscript Received: 30 NOV 2009
- basketball player;
- glutathione peroxidase;
- oxidative stress;
- maximal training;
- vitamins C and E
Oxidative stress occurs during maximal exercise, perhaps as a result of increased consumption of oxygen. Vitamins C and E can overcome the effects of antioxidants in exercise. We investigated the effects of supplementation with a combination of vitamin C and E (VCE) on blood lipid peroxidation (LP) and antioxidant levels following maximal training in basketball players.
Blood samples were taken from 14 players (group A) and divided into two subgroups namely maximal training (group B) and maximal training plus VCE groups (group C). Group B maximally exercised for 35 days. VCE was supplemented to group C for 35 days and blood samples were taken from group B and C. Plasma and hemolyzed erythrocyte samples were obtained from the players.
Erythrocyte glutathione peroxidase (GSH-Px) activity and plasma vitamin E concentration were lower in group B than in group A, whereas plasma and erythrocyte LP levels were higher in group B than in group A. Plasma vitamin A, vitamin E, erythrocyte GSH-Px, and reduced glutathione (GSH) values were higher in group C than in groups A and B although LP levels in plasma and erythrocytes were lower in group C than in group A and B. β-Carotene values did not change in the three groups.
In conclusion, VCE supplementation in maximal exercising basketball players may strengthen the antioxidant defense system by decreasing reactive oxygen species (ROS). Copyright © 2010 John Wiley & Sons, Ltd.