Research Article

Oral vitamin C and E combination modulates blood lipid peroxidation and antioxidant vitamin levels in maximal exercising basketball players

  1. Mustafa Nazıroğlu1,†,*,
  2. Fatih Kılınç2,
  3. Abdulhadi Cihangir Uğuz1,
  4. Ömer Çelik1,
  5. Ramazan Bal3,
  6. Peter J. Butterworth4,
  7. Metin Lütfi Baydar5

Article first published online: 7 MAY 2010

DOI: 10.1002/cbf.1657

Issue

Cell Biochemistry and Function

Cell Biochemistry and Function

Volume 28, Issue 4, pages 300–305, June 2010

Additional Information

How to Cite

Nazıroğlu, M., Kılınç, F., Uğuz, A. C., Çelik, Ö., Bal, R., Butterworth, P. J. and Baydar, M. L. (2010), Oral vitamin C and E combination modulates blood lipid peroxidation and antioxidant vitamin levels in maximal exercising basketball players. Cell Biochemistry and Function, 28: 300–305. doi: 10.1002/cbf.1657

Author Information

  1. 1

    Department of Biophysics, Medical Faculty, Suleyman Demirel University, Isparta, Turkey

  2. 2

    School of Physical Education and Sport, Suleyman Demirel University, Isparta, Turkey

  3. 3

    Department of Physiology, Medical Faculty, Firat University, Elazig, Turkey

  4. 4

    Nutritional Sciences Division, King's College London, UK

  5. 5

    Department of Sports Medicine, Medical Faculty, Süleyman Demirel University, Isparta, Turkey

  1. †

    Head of the Department.

*Department of Biophysic, Medical (TIP) Faculty, Süleyman Demirel University, TR-32260 Isparta, Turkey.

Publication History

  1. Issue published online: 26 MAY 2010
  2. Article first published online: 7 MAY 2010
  3. Manuscript Revised: 10 FEB 2010
  4. Manuscript Accepted: 10 FEB 2010
  5. Manuscript Received: 30 NOV 2009

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Keywords:

  • basketball player;
  • glutathione peroxidase;
  • oxidative stress;
  • maximal training;
  • vitamins C and E

Abstract

Oxidative stress occurs during maximal exercise, perhaps as a result of increased consumption of oxygen. Vitamins C and E can overcome the effects of antioxidants in exercise. We investigated the effects of supplementation with a combination of vitamin C and E (VCE) on blood lipid peroxidation (LP) and antioxidant levels following maximal training in basketball players.

Blood samples were taken from 14 players (group A) and divided into two subgroups namely maximal training (group B) and maximal training plus VCE groups (group C). Group B maximally exercised for 35 days. VCE was supplemented to group C for 35 days and blood samples were taken from group B and C. Plasma and hemolyzed erythrocyte samples were obtained from the players.

Erythrocyte glutathione peroxidase (GSH-Px) activity and plasma vitamin E concentration were lower in group B than in group A, whereas plasma and erythrocyte LP levels were higher in group B than in group A. Plasma vitamin A, vitamin E, erythrocyte GSH-Px, and reduced glutathione (GSH) values were higher in group C than in groups A and B although LP levels in plasma and erythrocytes were lower in group C than in group A and B. β-Carotene values did not change in the three groups.

In conclusion, VCE supplementation in maximal exercising basketball players may strengthen the antioxidant defense system by decreasing reactive oxygen species (ROS). Copyright © 2010 John Wiley & Sons, Ltd.

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