Minireview

Peptide Arrays for Kinase Profiling

  1. Mike Schutkowski Dr.1,
  2. Ulrich Reineke Dr.2,
  3. Ulf Reimer Dr.2

Article first published online: 1 MAR 2005

DOI: 10.1002/cbic.200400314

Issue

ChemBioChem

ChemBioChem

Special Issue: Kinases in Drug Discovery

Volume 6, Issue 3, pages 513–521, March 4, 2005

Additional Information

How to Cite

Schutkowski, M., Reineke, U. and Reimer, U. (2005), Peptide Arrays for Kinase Profiling. ChemBioChem, 6: 513–521. doi: 10.1002/cbic.200400314

Author Information

  1. 1

    JPT Peptide Technologies GmbH, Invalidenstraße 130, 10115 Berlin, Germany, Fax: (+49) 30-978-931-05

  2. 2

    Jerini AG, Invalidenstraße 130, 10115 Berlin, Germany

Publication History

  1. Issue published online: 1 MAR 2005
  2. Article first published online: 1 MAR 2005
  3. Manuscript Received: 7 SEP 2004

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Keywords:

  • enzymes;
  • kinases;
  • microarrays;
  • peptides;
  • SPOT synthesis;
  • substrate specificity

Graphical Abstract

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Hundreds and thousands of simultaneous kinase assays are possible by using peptide arrays. In this minireview, we summarize production principles, library types, and assay strategies used for kinase profiling on peptide arrays. The second part gives a comprehensive review of the various peptide microarray applications in kinase research.

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