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Keywords:

  • amino acids;
  • biosynthesis;
  • fusarin C;
  • isotopic labeling;
  • PKS/NRPS
Thumbnail image of graphical abstract

Fungal PKS/NRPS: [1,2-13C2,15N]-L-Homoserine has been prepared from [13C2,15N]-glycine in good yield. Incubation studies with cultures of the fungus Fusarium moniliforme confirm its intact incorporation into the pyrrolidinone ring of fusarin C.