Communication

Effects of Silicon Nanowires on HepG2 Cell Adhesion and Spreading

  1. Suijian Qi1,
  2. Changqing Yi1,
  3. Weiwei Chen Dr.2,
  4. Chi-Chun Fong Dr.1,
  5. Shuit-Tong Lee Prof.2,
  6. Mengsu Yang Prof. Dr.1

Article first published online: 24 MAY 2007

DOI: 10.1002/cbic.200700119

Issue

ChemBioChem

ChemBioChem

Volume 8, Issue 10, pages 1115–1118, July 9, 2007

Additional Information

How to Cite

Qi, S., Yi, C., Chen, W., Fong, C.-C., Lee, S.-T. and Yang, M. (2007), Effects of Silicon Nanowires on HepG2 Cell Adhesion and Spreading. ChemBioChem, 8: 1115–1118. doi: 10.1002/cbic.200700119

Author Information

  1. 1

    Department of Biology and Chemistry, City University of Hong Kong, Hong Kong SAR, China, Fax: (+852) 2788-7406

  2. 2

    Center of Super-Diamond and Advanced Films and Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, China, Fax: (+852) 2784-4696

Publication History

  1. Issue published online: 29 JUN 2007
  2. Article first published online: 24 MAY 2007
  3. Manuscript Received: 13 MAR 2007

Funded by

  • Research Grants Council of Hong Kong SAR, China. Grant Number: CityU 3/04C

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Keywords:

  • cell adhesion;
  • cytotoxicity;
  • nanostructures;
  • silicon

Graphical Abstract

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Brought to a halt. Scanning electron microscopy and energy dispersive X-ray spectroscopy were used to examine morphology and silicon content around HepG2 cells treated with silicon nanowires. Morphological changes and alterations in adhesion and spreading were found to be associated with silicon around the cell bodies. The results show that silicon nanowires do not favor HepG2 cell adhesion and spreading (see figure).

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