Spontaneous Generation of Giant Liposomes from an Oil/Water Interface

Authors

  • Ayako Yamada,

    1. Department of Physics, Graduate School of Science, Kyoto University, Kitashirakawa Oiwake-cho, Sakyo-ku, Kyoto 606-8502, Japan
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  • Maël Le Berre,

    1. Department of Chemistry, Ecole Normale Supérieure, 24 rue Lhomond, 75005 Paris, France, Fax: (+33) 1-4432-2402
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  • Kenichi Yoshikawa Prof.,

    1. Department of Physics, Graduate School of Science, Kyoto University, Kitashirakawa Oiwake-cho, Sakyo-ku, Kyoto 606-8502, Japan
    2. Spatio-Temporal Order Project, ICORP, JST, Department of Physics, Kyoto University, Kyoto 606-8502, Japan
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  • Damien Baigl Dr.

    1. Department of Chemistry, Ecole Normale Supérieure, 24 rue Lhomond, 75005 Paris, France, Fax: (+33) 1-4432-2402
    2. Spatio-Temporal Order Project, ICORP, JST, Department of Physics, Kyoto University, Kyoto 606-8502, Japan
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Abstract

original image

Sizing up liposomes. Giant liposomes (see image) were observed to spontaneously form when a horizontal liquid interface was made between an upper oil phase containing DOPC phospholipid and a lower water phase. This phenomenon depends on temperature and phospholipid concentration and it can be exploited to prepare cell-sized liposomes in a very simple fashion.

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