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Keywords:

  • amines;
  • asymmetric synthesis;
  • enzyme catalysis;
  • pyruvate decarboxylase;
  • transaminase
Thumbnail image of graphical abstract

Two is better than one (enzyme). The combination of ω-transaminase with pyruvate decarboxylase (PDC) allowed for the efficient asymmetric synthesis of chiral amines, because the unfavorable equilibrium could be shifted by removal of pyruvate by using PDC.