1439-7633/asset/2268_left.gif?v=1&s=307233408e54255dc0d91f8b45dbcbc9d91c02fb)
1439-7633/asset/2268_right.gif?v=1&s=3d91b10da22cd11de4d8c9a972145ff16791ee1f)
Communication
Two Base Pair Duplexes Suffice to Build a Novel Material
Article first published online: 6 MAY 2009
DOI: 10.1002/cbic.200900162
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Meng, M., Ahlborn, C., Bauer, M., Plietzsch, O., Soomro, S. A., Singh, A., Muller, T., Wenzel, W., Bräse, S. and Richert, C. (2009), Two Base Pair Duplexes Suffice to Build a Novel Material. ChemBioChem, 10: 1335–1339. doi: 10.1002/cbic.200900162
Publication History
- Issue published online: 14 MAY 2009
- Article first published online: 6 MAY 2009
- Manuscript Received: 20 MAR 2009
Funded by
- CFN. Grant Number: No.C5.1–3
Keywords:
- assembly;
- DNA;
- hybrids;
- nanostructures;
- oligonucleotides
Graphical Abstract
Tetrahedral DNA hybrids with tetrakis(p-hydroxyphenyl)methane cores hybridize in a sequence-specific fashion at much higher temperatures than isolated linear duplexes. Dinucleotide DNA arms suffice to induce the formation of a solid at room temperature; this demonstrates the strength of multivalent binding. The graphic shows a view of a modeled assembly.
Abstract
Tetrahedral DNA hybrids with tetrakis(p-hydroxyphenyl)methane cores hybridize in a sequence-specific fashion at much higher temperatures than isolated linear duplexes. Dinucleotide DNA arms suffice to induce the formation of a solid at room temperature; this demonstrates the strength of multivalent binding. The graphic shows a view of a modeled assembly.