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Keywords:

  • DNA structures;
  • gold;
  • inorganic binding peptides;
  • nanoparticles;
  • protein engineering;
  • self-assembly
Thumbnail image of graphical abstract

The golden age of DNA: We describe a strategy for engineering bifunctional proteins that simultaneously associate with metals and DNA to create self-assembled nanostructures. A DNA binding protein engineered with a gold binding peptide arranges colloidal gold particles along a DNA guide by virtue of its introduced peptide motif. These self-assembled complexes represent a step toward constructing nanoarchitectures with potential in nanoelectronic and photonic devices.