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Keywords:

  • aptamers;
  • gene expression;
  • riboswitches;
  • RNA switch;
  • TAR–RNA
Thumbnail image of graphical abstract

Controlling gene expression: An artificial gene regulation system operating at the transcriptional level in human cells and based on allosteric control of an RNA–protein interaction with the aid of a small ligand has been constructed. This system could be regarded as an artificial RNA switch.