SEARCH

SEARCH BY CITATION

Keywords:

  • diterpene cyclases;
  • enzymes;
  • natural products;
  • terpene synthases;
  • terpenoids
Thumbnail image of graphical abstract

Two-in-one enzyme: A bifunctional diterpene synthase from the lycophyte Selaginella moellendorffii has been characterized. The structure of its product, labda-7,13E-dien-15-ol, demonstrates that this enzyme catalyzes a novel class II diterpene cyclization reaction, and clarifies the biosynthetic origins of the family of derived natural products.