Identification of a Gene Cluster that Initiates Azasugar Biosynthesis in Bacillus amyloliquefaciens

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Abstract

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Am-aza-ing molecules! The archetypes for innumerable glycosidase inhibitors, azasugars, were first identified over 40 years ago. These deceptively simple molecules' biosynthetic machinery is only now being identified, and with this comes the opportunity to characterize several interesting monosaccharide transformations in the future.

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