These authors contributed equally to this work.
Inside Cover: Inhibition of Influenza Virus Activity by Multivalent Glycoarchitectures with Matched Sizes (ChemBioChem 6/2011)
Version of Record online: 6 APR 2011
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 12, Issue 6, page 814, April 11, 2011
How to Cite
Papp, I., Sieben, C., Sisson, A. L., Kostka, J., Böttcher, C., Ludwig, K., Herrmann, A. and Haag, R. (2011), Inside Cover: Inhibition of Influenza Virus Activity by Multivalent Glycoarchitectures with Matched Sizes (ChemBioChem 6/2011). ChemBioChem, 12: 814. doi: 10.1002/cbic.201190022
- Issue online: 6 APR 2011
- Version of Record online: 6 APR 2011
- Cited By
- multivalent inhibition;
- sialic acids;
The inside cover picture shows polyglycerol-based nanogels (~50 nm, blue) functionalized with sialic acid residues (orange). These glycocalyx mimetics are excellent inhibitors of influenza virus (green) binding and fusion. The optimal multivalent inhibitor reduces viral activity by up to 80 %; this emphasizes the importance of particle dimension and polyvalency for efficient competition with the cell surface (yellow). For further information, see the paper by R. Haag et al. on p. 887 ff.