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Keywords:

  • adenylation;
  • aminocoumarins;
  • biosynthesis;
  • enzymes;
  • MbtH;
  • rubradirin
Thumbnail image of graphical abstract

Master of your domain: A domain of the bifunctional enzyme RubC1 catalyzes the adenylation of tyrosine. This domain can be activated not only by MbtH-like proteins but also by another domain of RubC1 that has no similarity to MbtH-like proteins.