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Keywords:

  • FRET;
  • G protein-coupled receptors;
  • gamma-aminobutyric acid;
  • multiprobes;
  • Snifit
Thumbnail image of graphical abstract

Shedding light on GPCRs: A milestone in analyzing GPCRs, GABA-Snifit, reported by the Johnsson lab, integrates the advantages of both protein tags and fluorescent ligands. This cutting-edge technology opens up an avenue to the generation of GPCR-based fluorescent sensors, thus accelerating further study of GPCRs.