Enzymatic Aerobic Alkene Cleavage Catalyzed by a Mn3+-Dependent Proteinase A Homologue (pages 2427–2430)
Dr. Aashrita Rajagopalan, Dr. Markus Schober, Anita Emmerstorfer, Lucas Hammerer, Anna Migglautsch, Dr. Birgit Seisser, Dr. Silvia. M. Glueck, Dr. Frank Niehaus, Dr. Juergen Eck, Dr. Harald Pichler, Prof. Dr. Karl Gruber and Prof. Dr. Wolfgang Kroutil
Article first published online: 4 NOV 2013 | DOI: 10.1002/cbic.201300601
New clothes for Mn3+: Aerobic alkene cleavage of styrene-type substrates by Trametes hirsuta is attributed to an enzyme that is dependent on manganese in oxidation state three. The enzyme has a proteinase backbone and binds Mn3+ exclusively via oxygen atoms, in contrast to all known Mn3+ enzymes.