A Versatile Gold Surface Approach for Fabrication and Interrogation of Glycoarrays (pages 1568–1575)
Zheng-Liang Zhi, Nicolas Laurent, Andrew K. Powell, Rositsa Karamanska , Margherita Fais , Josef Voglmeir, Adam Wright, Jonathan M. Blackburn, Paul R. Crocker, David A. Russell, Sabine Flitsch, Rob A. Field and Jeremy E. Turnbull
Article first published online: 18 JUN 2008 | DOI: 10.1002/cbic.200700788
Glycoarrays on gold: A designer gold surface incorporating a self-assembled monolayer with weak protein absorption properties has been optimised for rapid display and interrogation of both native and derivatised glycans in array formats. This rapid, facile approach has diverse applications in glycomics, through exploitation of fluorescence, SPR and MALDI-ToF MS detection methods.