Coronary Artery Disease
Drug-eluting stenting is superior to bare metal stenting in saphenous vein grafts
Article first published online: 3 NOV 2005
Copyright © 2005 Wiley-Liss, Inc.
Catheterization and Cardiovascular Interventions
Volume 66, Issue 4, pages 507–511, December 2005
How to Cite
Lee, M. S., Shah, A. P., Aragon, J., Jamali, A., Dohad, S., Kar, S. and Makkar, R. R. (2005), Drug-eluting stenting is superior to bare metal stenting in saphenous vein grafts. Cathet. Cardiovasc. Intervent., 66: 507–511. doi: 10.1002/ccd.20498
- Issue published online: 21 NOV 2005
- Article first published online: 3 NOV 2005
- Manuscript Accepted: 31 MAY 2005
- Manuscript Received: 22 DEC 2004
- drug-eluting stent;
- percutaneous coronary intervention;
- saphenous vein graft
This study compared the outcomes of percutaneous coronary intervention (PCI) of saphenous vein grafts (SVGs) with drug-eluting stents (DES) with bare metal stents (BMS). PCI of degenerated SVG is associated with worse outcomes and high incidence of in-stent restenosis compared with PCI of native coronary arteries. There is a paucity of data on the outcomes of PCI of SVG with DES. Data from 223 consecutive patients who underwent PCI of SVG were imputed into a dedicated clinical database. We assessed the clinical outcomes at a mean follow-up of 9.1 ± 2.1 months. A total of 139 patients underwent PCI of SVG with DES and 84 patients with BMS. The mean age of the SVG was 7.6 ± 3.8 years in the DES group and 7.7 ± 2.8 years in the BMS group (P = 0.38). Procedural success was achieved in all patients except for one patient in the BMS group who underwent emergent coronary artery bypass graft surgery for SVG dissection. There were no other in-hospital cardiac events in both groups. There was one cardiac death in the DES group and three deaths in the BMS group (P = 0.03). When compared to the BMS, PCI of SVG with DES was associated with a lower incidence of myocardial infarction (4.3% vs. 20.2%; P = 0.04) and target vessel revascularization (10.1% vs. 36.9%; P = 0.035). When compared with BMS, PCI of SVG with DES was associated with a lower incidence of death, myocardial infarction, and target vessel revascularization. © 2005 Wiley-Liss, Inc.