Conflict of interest: Nothing to report.
Valvular and Structural Heart Diseases
Preclosure of large-sized venous access sites in adults undergoing transcatheter structural interventions
Version of Record online: 8 NOV 2012
Copyright © 2012 Wiley Periodicals, Inc.
Catheterization and Cardiovascular Interventions
Volume 81, Issue 4, pages 586–590, March 2013
How to Cite
Hamid, T., Rajagopal, R., Pius, C., Clarke, B. and Mahadevan, V. S. (2013), Preclosure of large-sized venous access sites in adults undergoing transcatheter structural interventions. Cathet. Cardiovasc. Intervent., 81: 586–590. doi: 10.1002/ccd.24358
- Issue online: 22 FEB 2013
- Version of Record online: 8 NOV 2012
- Accepted manuscript online: 16 MAR 2012 10:46AM EST
- Manuscript Accepted: 2 FEB 2012
- Manuscript Received: 22 OCT 2011
- femoral vein;
- vascular closure devices;
- vascular complications;
Patients requiring congenital and structural heart interventions often require large-sized sheath insertion into femoral veins and arteries. Clinical outcome data on the use of suture-mediated devices for femoral venous access site closure are limited.
To assess the efficacy and safety of the Perclose™ (Abbott Vascular Devices, CA) suture-mediated device using the preclosure technique, in achieving haemostasis at femoral venous access site following large sheath insertion (≥8 Fr).
Design and Setting
Two hundred and forty-three consecutive patients underwent 310 access site closures with the Perclose™ device using the preclosure technique. There were 151 (62%) women, mean age 43 (±16) years. 234/243 (96%) received heparin. Mean venous access site sheath diameter was 11.5 (±3) Fr.
Immediate haemostasis (<2 min) was achieved in 304/310 (98%) sites. No patients had major complications. Short-term follow-up at 3 months revealed no evidence of haematoma or fistula formation or clinical evidence of vessel occlusion. On medium-term clinical follow-up (mean follow-up of 14 ± 12 and median of 12.4 months), no complications were seen at the venous access sites.
Preclosure of large-size femoral venous access sheath sites using the suture-mediated Perclose™ device is efficacious in achieving rapid haemostasis in the presence of anticoagulation in the venous site. On 1-year follow-up, there was no clinical evidence of vascular complications in the venous access sites. © 2012 Wiley Periodicals, Inc.