Conflict of interest: Nothing to report.
Pediatric and Congenital Heart Disease
Postimplant complications with transcatheter closure of congenital perimembranous ventricular septal defects
A single-center, longitudinal study from 2002 to 2011
Article first published online: 14 FEB 2013
Copyright © 2012 Wiley Periodicals, Inc.
Catheterization and Cardiovascular Interventions
Volume 81, Issue 4, pages 666–673, March 2013
How to Cite
Jin, Y., Han, B., Zhang, J., Zhuang, J., Yan, J. and Wang, Y. (2013), Postimplant complications with transcatheter closure of congenital perimembranous ventricular septal defects. Cathet. Cardiovasc. Intervent., 81: 666–673. doi: 10.1002/ccd.24638
- Issue published online: 22 FEB 2013
- Article first published online: 14 FEB 2013
- Accepted manuscript online: 31 AUG 2012 03:44AM EST
- Manuscript Accepted: 26 AUG 2012
- Manuscript Received: 17 FEB 2012
- interventional treatment;
- perimembranous ventricular septal defect;
- retrospectively comparative analysis
Whether or not to close perimembranous VSDs (pmVSDs) by transcatheter techniques is controversial because of a high rate of complications as compared with surgical alternatives.
We report the short- and long-term follow-up results of the use of several kinds of devices to close pmVSDs and the annual incidence of postimplant complications in our center.
From June 2002 to June 2011, 232 patients with pmVSD underwent attempted transcatheter closure; closure was successful in 209 cases (90.1%). Six types of occlusive devices were used. Patient age, defect size, device type, device size and its relation to defect size, and transcatheter and fluoroscopy time were analyzed for correlation with annual incidence of postimplant complications.
There were no deaths during the follow-up period. Within 1 month after transcatheter closure, we found 91 adverse events (43.5%), but only 32 cases showed a trace amount of residual shunting. From 2002 to 2011, the annual incidence of postimplant complications gradually decreased, from 50% in 2002 to 17.6% in 2011. The use of Amplatzer occluder devices (r = 0.71, P = 0.033), double-disc symmetrical occluder devices (r = −0.68, P = 0.045), and transcatheter (r = 0.87, P = 0.003), and fluoroscopy time (r = 0.78, P = 0.02) were significantly correlated with the incidence of post-implant complications.
Results of transcatheter closure of pmVSD in terms of postimplant complications are encouraging in our center. It seemed that eccentric Amplatzer and domestic occluder may be at rather higher risk for postimplant complications. The incidence of postimplant complications may be minimized by skilled maneuvers, excluding rather small patients, and selecting the appropriate kind of occlusive device. © 2012 Wiley Periodicals, Inc.