Conflict of interest: Nothing to report.
E-ONLY: Coronary Artery Disease
Porcine model of intracoronary pulverization of stent struts by rotablation atherectomy
Article first published online: 2 SEP 2013
Copyright © 2012 Wiley Periodicals, Inc.
Catheterization and Cardiovascular Interventions
Volume 82, Issue 7, pages E842–E848, 1 December 2013
How to Cite
Quang, T. T., Hatem, R., Rousseau, G., Dube, B., Samson, C., Schampaert, E. and Charron, T. (2013), Porcine model of intracoronary pulverization of stent struts by rotablation atherectomy. Cathet. Cardiovasc. Intervent., 82: E842–E848. doi: 10.1002/ccd.24650
- Issue published online: 20 NOV 2013
- Article first published online: 2 SEP 2013
- Accepted manuscript online: 4 SEP 2012 12:59AM EST
- Manuscript Accepted: 30 AUG 2012
- Manuscript Received: 13 FEB 2012
- Centre de recherche
- Hôpital du Sacré-Coeur de Montréal
- Fonds de la recherche en santé du Québec (FRSQ)
- distal embolization;
- vascular bed
To evaluate the feasibility and safety of rotablation atherectomy in a suboptimally expanded stent.
Seven pigs underwent suboptimal stent expansion in the left anterior descending coronary. Pulverization of the stent struts was performed by rotablation atherectomy with two different burr sizes. Two types of control porcine models were used: pigs with fully expanded stents and pigs without stents. Continuous electrocardiogram readings as well as microscopic and radiologic analysis of cardiac tissue were performed.
Rotablation atherectomy reduces the suboptimally expanded stent by (26.95 ± 5.03)%. Ninety-five percent of the metal microparticles, imbedded in the suboptimally expanded stent group cardiac tissue, are less than 15 μm. Transient vasospasm and ST segments elevations were observed during rotablation atherectomy, which returned to basal conditions at the end of the intervention.
Our study demonstrated the feasibility and safety of using rotablation atherectomy to pulverize stent struts in a suboptimally expanded stent. © 2012 Wiley Periodicals, Inc.