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Clinical Case Reports

Cover image for Vol. 1 Issue 1

October 2013

Volume 1, Issue 1

Pages i–ii, 1–45

  1. Issue Information

    1. Top of page
    2. Issue Information
    3. Editorial
    4. Case Reports
    5. Clinical Images
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      Issue Information (pages i–ii)

      Article first published online: 25 OCT 2013 | DOI: 10.1002/ccr3.24

  2. Editorial

    1. Top of page
    2. Issue Information
    3. Editorial
    4. Case Reports
    5. Clinical Images
    1. You have full text access to this OnlineOpen article
  3. Case Reports

    1. Top of page
    2. Issue Information
    3. Editorial
    4. Case Reports
    5. Clinical Images
    1. You have full text access to this OnlineOpen article
      A perioperative uncontrollable bleeding in an elderly patient with acquired hemophilia A: a case report (pages 3–6)

      Andrea Cortegiani, Vincenzo Russotto, Grazia Foresta, Francesca Montalto, Maria Teresa Strano, Santi Maurizio Raineri and Antonino Giarratano

      Article first published online: 21 JUL 2013 | DOI: 10.1002/ccr3.2

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      A perioperative uncontrollable bleeding referable to an acquired hemophilia A, characterized by a high factor VIII inhibitors titer and a very poor response to bypassing agents and immunosuppressive therapy.

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      Reversal of experimental paralysis in a human by intranasal neostigmine aerosol suggests a novel approach to the early treatment of neurotoxic envenomation (pages 7–15)

      Matthew R. Lewin, Philip Bickler, Tom Heier, John Feiner, Lance Montauk and Brett Mensh

      Article first published online: 24 JUL 2013 | DOI: 10.1002/ccr3.3

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      We describe the reversal of experimental paralysis using nasal spray neostigmine in a healthy human volunteer. The development of a heat-stable, inexpensive antidote to neurotoxins could save lives in the setting of snakebite or other neurotoxic envenomations. Current treatments are generally limited to hospitals and clinics with antivenins and intensive care capabilities. Our findings suggest a novel approach to the treatment of neurotoxic and other snakebites warranting further investigation.

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      Lesions more than cerebellum in a puerpera of acute cerebellitis: concurrent encephalitis, not a subtype of ADEM (pages 16–19)

      Yong-Qing Zhang, Dan Chen, Ya-Fen Zou, Ming Huang and Xiao-Yan Jia

      Article first published online: 31 JUL 2013 | DOI: 10.1002/ccr3.4

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      Acute cerebellitis is rare in adult and its lesions are usually confined in cerebellum. We report a puerpera who has typical clinical features, with multiple lesions beyond cerebellum. This lead to the diagnosis of concurrent encephalitis.

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      Reversible ventricular arrythmia induced by dasatinib (pages 20–25)

      Hervé Spechbach, Philippe Morel, Kuntheavy Ing Lorenzini, Marie Besson, Laurent Gétaz, Henri Sunthorn and Yves Chalandon

      Article first published online: 31 JUL 2013 | DOI: 10.1002/ccr3.5

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      Ventricular arrhythmias induced by dasatinib are rare events, but physicians in charge of chronic myeloid leukemia patients should be aware of such potential complications and the need for regular ECG controls during treatment with tyrosine kinase inhibitors.

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      Multiple bone metastases detected 10 years after mastectomy with silicone reconstruction for DCIS and contralateral augmentation (pages 26–29)

      Ryutaro Mori and Yasuko Nagao

      Article first published online: 29 AUG 2013 | DOI: 10.1002/ccr3.7

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      Multiple bone metastases were detected after treatment for ductal carcinoma in situ (DCIS). Contralateral invasive breast cancer was considered to be the metastatic origin.

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      Complex cytogenetic rearrangements at the DURS1 locus in syndromic Duane retraction syndrome (pages 30–37)

      Hagit N. Baris, Wai-Man Chan, Caroline Andrews, Doron M. Behar, Diana J. Donovan, Cynthia C. Morton, Judith Ranells, Tuya Pal, Azra H. Ligon and Elizabeth C. Engle

      Article first published online: 30 SEP 2013 | DOI: 10.1002/ccr3.11

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      A patient with syndromic Duane retraction syndrome harbors a chromosome 8p11.1q13.2 inversion and 8p11.1-q12.3 marker chromosome containing subregions with differing mosaicism and allele frequencies. This case highlights the potential requirement for multiple genetic methods to gain insight into genotype–phenotype correlation, and ultimately into molecular mechanisms that underlie human disease.

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      Pregnancy complicated by focal nodular hyperplasia: a case report of one woman over two consecutive courses of pregnancy (pages 38–41)

      Yousuke Gomi, Kenjiro Takagi, Shigetaka Matunaga, Hideyoshi Matsumura, Masahiro Saito and Hiroyuki Seki

      Article first published online: 30 SEP 2013 | DOI: 10.1002/ccr3.17

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      We encountered a woman with a preexisting large focal nodular hyperplasia (FNH) of the liver, persisting during two separate pregnancies. FNH size was not affected by either pregnancy. Her elevated serum γ-glutamyltransferase and alkaline phosphatase levels before pregnancy were reduced during both pregnancies, but returned to prepregnancy levels after delivery.

  4. Clinical Images

    1. Top of page
    2. Issue Information
    3. Editorial
    4. Case Reports
    5. Clinical Images
    1. You have full text access to this OnlineOpen article
      Wandering spleen: a potential abdominal catastrophe (pages 42–43)

      Anthony McBrearty, Etain McGuinness and Adrian Neill

      Article first published online: 4 SEP 2013 | DOI: 10.1002/ccr3.9

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      We describe a case of wandering spleen complicated by splenic volvulus and present the abnormal CT and intraoperative imaging to highlight the difficulties in managing this rare condition.

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      What is the diagnosis for this rash? (page 44)

      Namrata Singh and Shireesh Saurabh

      Article first published online: 9 SEP 2013 | DOI: 10.1002/ccr3.10

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      A 46-year-old female with history of Churg-Strauss syndrome was seen for a flare-up. The rash that she presented with was because of traditional practice called “coining” and this can be confused with physical abuse especially in children and a careful history is needed.

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      Lower extremity mass (page 45)

      Shireesh Saurabh and Namrata Singh

      Article first published online: 24 SEP 2013 | DOI: 10.1002/ccr3.12

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      Soft tissue sarcomas are rare tumors accounting for less than 1% of all malignancies. Multidisciplinary approach is used in the management of these patients.

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