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Keywords:

  • Crook's cell adenoma;
  • Cushing's disease;
  • temozolamide.

Key Clinical Message

The clinical course of our patient, who sustained remission status for at least 18 months highlights the chance of long-term hormonal and tumor remission and demonstrates the efficacy and safety of discontinuation of temozolomide therapy. Prospective studies are required in order to define predictors of long-term remission of this promising therapeutic modality.