Chronic myelomonocytic leukemia presenting with polyserositis due to an immune-mediated monocyte activation
Article first published online: 28 FEB 2014
© 2014 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.
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Clinical Case Reports
Volume 2, Issue 2, pages 42–44, April 2014
How to Cite
Clinical Case Reports 2014; 2(2): 42–44
- Issue published online: 9 APR 2014
- Article first published online: 28 FEB 2014
- Manuscript Accepted: 25 JAN 2014
- Manuscript Revised: 21 DEC 2013
- Manuscript Received: 17 AUG 2013
- Chronic myelomonocytic leukemia;
- myelodysplastic syndrome;
- myeloproliferative neoplasm;
Key Clinical Message
Monocytosis is often profoundly implicated in chronic myelomonocytic leukemia (CMML). We diagnosed a 63-year-old woman with CMML involving heterochronological systemic polyserositis with infiltrating benign monocytes. The patient's pleural effusion was eliminated completely with corticosteroid therapy. We speculate that our case represents an immunological reaction with activated monocytes triggered by infection.