Hyperacute ischemic stroke without lesions on diffusion-weighted imaging in a patient treated with rtPA thrombolysis
Article first published online: 16 MAR 2014
© 2014 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.
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Clinical Case Reports
Volume 2, Issue 3, pages 70–73, June 2014
How to Cite
Clinical Case Reports 2014; 2(3): 70–73
- Issue published online: 15 JUL 2014
- Article first published online: 16 MAR 2014
- Manuscript Accepted: 25 JAN 2014
- Manuscript Revised: 25 DEC 2013
- Manuscript Received: 3 AUG 2013
- National Nature Science Foundation of China. Grant Number: 21312137
- Diffusion-weighted imaging;
- hyperacute ischemic stroke;
- recombinant tissue plasminogen activator;
Key Clinical Message
We report a comatose patient with severe neurological deficits who was without spontaneous language or movement. He had a good response to recombinant tissue plasminogen activator (rtPA) thrombolysis even though there were no detectable lesions on diffusion-weighted imaging (DWI). DWI is very sensitive for diagnosing hyperacute ischemic stroke, and rtPA thrombolysis is the best treatment. However, rtPA thrombolysis in ischemic stroke patients without lesions on DWI has rarely been reported.