Long-term survival in multiple myeloma
Article first published online: 28 MAY 2014
© 2014 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.
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Clinical Case Reports
How to Cite
João, C., Costa, C., Coelho, I., Vergueiro, M. J., Ferreira, M. and da Silva, M. G. (2014), Long-term survival in multiple myeloma. Clinical Case Reports. doi: 10.1002/ccr3.76
- Article first published online: 28 MAY 2014
- Manuscript Accepted: 15 APR 2014
- Manuscript Revised: 17 MAR 2014
- Manuscript Received: 16 FEB 2014
- Clinical characteristics in multiple myeloma;
- multiple myeloma long survivors;
Key Clinical Message
The survival of multiple myeloma patients has improved very significantly over the last decade. Still median overall survival is inferior to 5 years. A small proportion of patients survive longer than 10 years. In this paper we discuss four cases illustrating the nonhomogeneous clinical presentation and evolution of this subset of patients. Surprisingly, these long survivors do not always have deep responses and some require frequent treatments, which include autologous stem cell transplantation and novel drugs. The authors discuss several aspects of these clinical histories, including treatment options, raising hypothesis on their relation with long survivorship which may be important to have in consideration when studying this subject.