Cover Picture: Regioselective Hydroformylation of Styrene Using Rhodium-Substituted Carbonic Anhydrase (ChemCatChem 8/2010)

Authors

  • Qing Jing Dr.,

    1. Department of Biochemistry, Molecular Biology & Biophysics and the Biotechnology Institute, University of Minnesota, 1479 Gortner Avenue, Saint Paul, MN 55108 (USA), Fax: (+1) 612-625-5780
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  • Romas J. Kazlauskas Prof. Dr.

    1. Department of Biochemistry, Molecular Biology & Biophysics and the Biotechnology Institute, University of Minnesota, 1479 Gortner Avenue, Saint Paul, MN 55108 (USA), Fax: (+1) 612-625-5780
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Abstract

original image

The cover picture shows rhodium-substituted carbonic anhydrase. In their Communication on page 953 ff., Jing and Kazlauskas demonstrate how, by replacing the zinc center in carbonic anhydrase with rhodium, an enzyme is created that catalyzes the hydroformylation of styrene. The active-site-bound rhodium favors formation of the linear hydroformylation product, whereas the unbound rhodium favors the branched product. This is just one example of the great recent strides made in biocatalysis, as highlighted in this Special Issue.

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