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Cross-Coupling in the Preparation of Pharmaceutically Relevant Substrates using Palladium Supported on Functionalized Mesoporous Silicas



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Going back to black: Palladium-containing, organically functionalized, mesoporous silicas have been found to be efficient catalysts for the synthesis of functionalized compounds including pharmaceutical precursors in high yield with low levels of metal contamination. In cases where comparisons to reported Pd contamination are possible, our system is found to be significantly more effective.