A new door is open! Conceptually new organocatalytic enantioselective 1,6-addition reactions have recently been uncovered by the groups of Jørgensen, Alexakis, and Stephens. Key to their success was the design of appropriate organocatalyts and Michael acceptors with unique reactivities, which lead to highly regioselective and enantioselective products.
If you can't find a tool you're looking for, please click the link at the top of the page to "Go to old article view". Alternatively, view our Knowledge Base articles for additional help. Your feedback is important to us, so please let us know if you have comments or ideas for improvement.