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Simple and Sustainable Copper–O2 Chemistry towards High-Value Products

Authors

  • Dr. Miquel Costas

    Corresponding author
    1. Department of Chemistry, Universitat de Girona, Facultat de Ciències, Campus de Montilivi, 17071, Girona (Spain), Fax: (+34) 972-418150
    • Department of Chemistry, Universitat de Girona, Facultat de Ciències, Campus de Montilivi, 17071, Girona (Spain), Fax: (+34) 972-418150

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Abstract

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Oxygen meets its end, or does it? Straightforward Cu-catalyzed preparation of α-ketoamides has been recently achieved through oxidative coupling of aryl acetaldehydes and arylamines by using O2 as the terminal oxidant. The work represents a remarkable example of a simple and sustainable transformation to yield elaborate and more complex biologically relevant oxidized products from readily available reagents under mild conditions.

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