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para-Selective Aerobic Oxidative C[BOND]H Olefination of Aminobenzenes Catalyzed by Palladium/Molybdovanadophosphoric acid/2,4,6-Trimethylbenzoic Acid System

Authors

  • Yohei Mizuta,

    1. Department of Chemistry and Material Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, Suita, Osaka 564-8680 (Japan), Fax: (+81) 6-6339-4026
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  • Dr. Yasushi Obora,

    Corresponding author
    1. Department of Chemistry and Material Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, Suita, Osaka 564-8680 (Japan), Fax: (+81) 6-6339-4026
    • Department of Chemistry and Material Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, Suita, Osaka 564-8680 (Japan), Fax: (+81) 6-6339-4026

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  • Yosuke Shimizu,

    1. Department of Chemistry and Material Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, Suita, Osaka 564-8680 (Japan), Fax: (+81) 6-6339-4026
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  • Prof. Yasutaka Ishii

    1. Department of Chemistry and Material Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, Suita, Osaka 564-8680 (Japan), Fax: (+81) 6-6339-4026
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Abstract

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Pick of the bunch: Oxidative C[BOND]H olefination of aminobenzenes with acrylates was achieved using a palladium/molybdovanadophosphoric acid (HPMoV)/2,4,6-trimethylbenzoic acid (TMBA) system under O2 (1 atm) in DMF. The highly regio- and stereoselective C[BOND]H olefination of basic substrates such as aminobenzenes is important in organic synthesis; (E)-para-alkenyl-substituted aminobenzenes were produced in high yields.

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