Organocatalytic Enantioselective α-Alkylation of Aldehydes

Authors

  • Dr. Jan Vesely,

    Corresponding author
    1. Department of Organic Chemistry, Charles University in Prague, Hlavova 2030 (Czech Republic), Fax: (+42) 0221951326
    • Department of Organic Chemistry, Charles University in Prague, Hlavova 2030 (Czech Republic), Fax: (+42) 0221951326
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  • Prof. Dr. Ramon Rios

    Corresponding author
    1. Department of Organic Chemistry, University of Barcelona, Marti i Franques 1-11 (Spain)
    2. ICREA, Passeig Lluis Companys 23 (Spain)
    • Department of Organic Chemistry, University of Barcelona, Marti i Franques 1-11 (Spain)
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Abstract

original image

The knights that say enamine: Organocatalytic intermolecular α-alkylation has been a long awaited prize for organocatalytic chemists. Recently several research groups have reported several methodologies with high levels of stereoselectivity. In this Minireview we aim to describe the efforts made in this field in recent years.

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