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Keywords:

  • aldehydes;
  • amidation;
  • amines;
  • olefins;
  • rhodium
Thumbnail image of graphical abstract

Rhodium teaches toleration: The diolefin-amine–RhI complex [Rh(OTf)(trop2NH)(PPh3)] (see scheme) is an effective pre-catalyst for the amidation of a wide range of aldehydes with primary amines. The corresponding amides are obtained in good-to-excellent yields under very mild reactions conditions and a variety of functional groups are tolerated.