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Keywords:

  • heterogeneous catalysis;
  • nanomaterial;
  • one-pot reaction;
  • palladium;
  • quinoline

Abstract

The synthesis of quinolines has been achieved through a one-pot, two-step tandem reaction catalyzed with Ag[BOND]Pd alloy nanoparticles supported on carbon. Ag[BOND]Pd alloy nanoparticles catalyzed the coupling of a ketone with a primary alcohol through a hydrogen autotransfer process, which yields α-alkylated ketones under an Ar flow. These are reacted with 2-aminobenzyl alcohols in a modified Friedländer synthesis to give polysubstituted quinolines in moderate to good yields.