A Monovacant Lacunary Silicotungstate as an Efficient Heterogeneous Catalyst for Dehydration of Primary Amides to Nitriles

Authors

  • Shintaro Itagaki,

    1. Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan), Fax: (+81) 3-5841-7220
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  • Dr. Keigo Kamata,

    1. Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan), Fax: (+81) 3-5841-7220
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  • Dr. Kazuya Yamaguchi,

    1. Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan), Fax: (+81) 3-5841-7220
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  • Prof. Dr. Noritaka Mizuno

    Corresponding author
    1. Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan), Fax: (+81) 3-5841-7220
    • Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan), Fax: (+81) 3-5841-7220

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Abstract

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Acting up with nitriles: A monovacant lacunary silicotungstate, TBA4[α-H4SiW11O39] (I) could act as an efficient heterogeneous catalyst for dehydration of primary amides. Various kinds of primary amides, including benzylic, double bond-containing, heteroaromatic, and aliphatic could be converted into the corresponding nitriles in moderate to excellent yields.

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