SEARCH

SEARCH BY CITATION

Keywords:

  • amino acids;
  • asymmetric catalysis;
  • hydrogen bonds;
  • organocatalysis;
  • phosphanes

Abstract

This minireview focuses on the recent advances in the synthetic application of amino acid-derived bifunctional phosphine catalysts bearing a hydrogen-bond donor. In the examples illustrated, the amino acid-based phosphines have already been proven to be versatile, catalyzing a wide range of asymmetric reactions, including (aza)-MBH reactions, [3+2] cyclizations, [4+2] cycloadditions, allylic alkylation, and Michael addition.